Selection of IVF embryos for the normal number of chromosomes can significantly increase the pregnancy rate

Cambridge, UK (PRWeb) 3 May 2012
Blue Gnome Ltd. announced today that the first randomized prospective study, IVF implantation genetic diagnosis with 24sure array platform shows that the selection of euploid embryos implant with a normal number of chromosomes was significantly increased pregnancy rates. The study was published in the current edition of the Journal of Molecular cytogenetic Yang et al (Pacific Reproductive Center, Torrance, Calif.). This promising result gives much direct evidence 24sure analysis can deliver 65 percent higher interest rates during pregnancy, even in younger patients are more likely to have favorable results of IVF.
24sure screen all 24 chromosomes of the embryo in the sample, with a fast turnaround time (less than 12 hours) and with high accuracy and reliability, so that embryos with a normal number of chromosomes (euploid embryos) were selected for IVF cycles. Embryo decided aneuploid (containing incorrect number of chromosomes, or Down syndrome or trisomy 21) are capable of logical choices and not moved on in vitro fertilization cycles.
“This community is focused in PGD couples only with the meanings specified for testing (eg, advanced maternal age), and not in relation to aneuploidies occur in all IVF patients. This clearly shows the aneuploidy rate of 45% was found in embryos from young patients and may explain why many young women do not achieve pregnancy, even after transfer of embryos of good quality. new Array-CGH-based comprehensive chromosome screening technique has great promise for improving clinical outcomes of IVF for infertile each patient to choose the fittest embryo (s) to move, “said Dr. Francesco Fiorentino, CEO, Genome, Rome, Italy.
blind randomized study 103 IVF cycles. Trol group of 55 rounds and 5 24sure analyzing the primary outcome measure was used to screen for chromosomal abnormalities and specific implant a euploid fetus (as recommended by the IVF regulatory bodies such as the Human Fert Lisa virtualization in the UK and Embryology Authority), which controls 48 cycle, single embryos were selected using existing morphological methods scorecard. In the course of pregnancy after 20 weeks, the session was started, was 69.1% in 24sure treatment group vs. 41.7% in the control group. Further randomized studies are needed and are ongoing.
This study provides key evidence that chromosome 24 to chromosome screening 24sure can offer dramatic benefits of IVF success. Although further research is still needed, this finding is very exciting because it shows for the first screening of 24 chromosomes and one embryo transfer has the potential to become the default standard of care in all IVF cycles in the whole world, said Nick Haan, Chairman Blue Gnome Administration Ltd., Cambridge, United Kingdom
Link to research paper
http://www.molecularcytogenetics.org/content/5/1/24/abstract ~ ~ V
Video 24sure
http://www.youtube.com/watch?v=U38IjDFHQd8
Quotes from key opinion leaders
“24sure comprehensive chromosomal screening is scientifically proven to be an effective way to select chromosomally normal fetuses (s) for transfer to ensure a healthy pregnancy for infertile patients. As a clinical scientist, I am happy to be part of new technology.” – Dr. . Yang Zhihong, Executive Director, Arts and PGD Laboratories, Pacific Reproductive Center Torrance, CA
“This well designed study supports what many of us assumed for a long time, chromosomal aberrations are responsible for most of the failure of IVF-embryo pregnancy assessment capabilities to create the best do not morphological examination,., and this is best done evaluating all 24 chromosomes . This approach will lead to better patient outcomes. set a high potential of embryos will lead to fewer multiple pregnancies and fewer abortions, and will also help us to define the group of patients who make little or no euploid embryos. “- Jamie A. Grifo, MD, PhD, director of NYU Fertility Center, NY
“Many fertilized ova are genetic effects, even in young infertile couples. This study shows convincingly that the embryo is not able to detect microscopic evaluation alone. This center studies in two different countries highlights the importance of removing abnormal embryos for serious entry into the uterus through the so-called universal screening. modern form of preimplantation genetic screening, or PGS Although the study was relatively small, the results were blinded to the observer and the embryos were randomized to avoid bias opens exciting. ability to perform PGS, not only in more complex patients, such as those with poor ovarian reserve, as well as egg donors and young women abnormal embryos are common in all ages. “- Jacques Cohen, MD, director of Tyho-Galileo Research Laboratories, Livingston, New Jersey
“Calling Dr. Yang is incredible. We know that the rate of embryonic chromosomal abnormality in young patients as high as 40 percent, increasing to 70% in women blastocysts> 40th of their studies means that if young women benefit from blastocyst Sampling and 6 and the aCGH transferred, women of advanced age have more trouble conceiving, it will also, as they produce enough to make an embryo or embryo banking. In fact, in collaboration with Gary Hartola during Reprogenetics shown that if euploid blastocysts and transfer. Web at the same rate regardless of the age method, day 5 and day 6 biopsy transmission is more acceptable to patients, because they are less expensive than vitrification, and patients have to wait another cycle of time. “- Santiago Munn, MD, director of Reprogenetics, Livingston , New Jersey
“Although this small pilot study clearly points out that even the younger infertile couples IVF will greatly benefit from this powerful technology advance. Since nearly half of patients are chromosomally abnormal embryos, the ability to reliably distinguish between normal uterine they transfer impressive, will improve the chances that a fairly desperate couples can finally have a healthy family and one child at a time, which is the ultimate goal for everyone involved. “- Professor Mark Hughes, Genesis Genetics Institute, Detroit, MI
“This well-done study adds to growing evidence that the chromosome 24 from the field test CGH allows PGD finally reach their potential in order to find the best embryos with the highest and lowest insertion loss of central banks. Study Yang et al. confirms that the chromosome analysis is a series of CGH is the best method to identify developmentally competent embryos for ESET allies. “- Harvey J. Stern, MD, PhD, Director of Reproductive Genetics, Genetics and IVF Institute in Fairfax, VA
“This discovery is a clinical trial, showing for the first time that this technology, CARE has helped pioneer, may improve IVF success rates for younger patients. In fertility care, we have shown that implantation genetic screening has benefits for older patients and those with a complex story, so it’s great to see the scope of this technology could benefit many more patients. “- Professor Simon Fisher, director of CARE Fertility Group in the UK
“I’m not at all surprised by the good results from the California group. They reflect our success in Melbourne IVF with Blue dwarfs 24sure technology. We have provided this service to our patients for more than a year when about 20 children were born and another 50 are on the way This significant achievement for patients who are struggling to become pregnant. “-. Dr. Leeanda Wilton, Preimplantation Genetics Research Director, Melbourne IVF, Australia
Blue Gnome
based in Cambridge, UK, Blue Gnome is a leading provider of genetic screening for chromosomal abnormalities in cytogenetics and IVF.
http://
The National Parenting Center Award for the brand of your pregnancy pad for 2012 stamp of approval
Great Falls, VA (PRWeb) 3 May 2012
The National Parenting Center [TNPC] announced the winners of the 2012 seal of approval of full pregnancy pillow is your winner. Hundreds of products were delivered and underwent a thorough evaluation process first-hand consumer testing over ten weeks. The opinion can be located at TNPC initial TNPC.com.
Seal
National Center educational program approval is an independent testing procedure conducted to judge the variety of products introduced and marketed to the consumer market, the parent / child. Estimated level of desirability of each product and strength and other ingredients necessary to make a quality product. Results are based on both statistical averaging comments received from the testers.
complete your pregnancy pillow promises to provide the best comfort with special design. It comes in the form of a cube that opens in the form of two triangles. When in the open position, the two halves back support cushions and abdomen simultaneously. Ergonomic memory foam pillows on one side of the mother’s stomach. The second half of the pillow is a higher density foam for support, while keeping the body positioned on the side.
one of the biggest complaints of the restrictions on a pregnant woman that are too bulky to take up half the bed at night and no place to discreetly store the other day. Other issues that are too confining and do not provide the balance amount of aid the body.
complete your pregnancy pillow covers successfully all these problems and has already proven that pregnant mom restful sleep and reduce pain in the back of the pillow face before use. Pictures and video that can be viewed / downloaded http://www.utterlyyours.com/media.html HEAD ~ ~ = ~ ~ ~ Dobje HEAD Dobje = ~ = ~ ~ HEAD Dobje escape.
Here’s what the National Parenting Center had to say:
is pregnant, as it is an exciting time, full of anticipation and preparation. Other aspects of pregnancy are less optimistic, they are exhaustion, fatigue and discomfort. Find a comfortable position when doing something as simple as watching television may be impossible for some. Pregnancy Pillow is a support system that gives the mother in late pregnancy, some much needed help. Uniquely designed and shaped pillow is designed to support mothers to be when they are in downtime, such as lying on a couch, or even the floor and watch TV. Support for the back and abdomen, the sky and found to reduce discomfort. Visually find that attractive with a sweet and cool its content design. See through packaging, and concluded that the dice is considered pretty smart.
TNPC:
The National Parenting Center was founded in July 1989 with the aim of providing the most comprehensive and responsible parenting advice to parents everywhere. Consultants who created some of the world’s most respected authorities in the field of child education and development.
Seal
National Center of Education approval of the program, created in 1990 as a supplement to TNPC’s support services, identifies the finest products and services marketed by the parent / child audience. From educational and entertainment products and equipment for tourist destinations, consumer oriented testing process collects food from their parents and their children. The award is based on other parents what their peers have recognized the quality of products and preferably based on the number of determining factors.
This is the only intention of the National Parenting Center to advise, support and guide parents with sound, responsible advice.
core activities:
Your brand was founded in 2004, and was founded by a mom to help women overcome common problems faced by the state of motherhood in pregnancy and lactation. Agship their product – which is entirely your breast pad – designed for women who are physically support your breasts while nursing moms give a much simpler and hands-free way to succeed with this endeavor. Your Pregnancy core pillow is designed to reduce lower back / hip pain by women comfortably on their side, but also support their stomach during sleep. Both offer a product has received many awards and recommended OB / GYNs and lactation consultants worldwide. To learn more about or to order your child a pillow, visit http://www.utterlyyours.com.
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